I know that the clear vinyl comes in different gauges or thicknesses so I think you’ll be fine using a regular machine as long as you’re not using the heaviest vinyl the store carries. If you’re using the one of the lighter vinyls, you should be fine. I have sewn with this type of vinyl on my machine before and it was a little tricky as the vinyl seems to stick in place and not feed very smoothly under the machine foot. To get around this, I sandwich the vinyl in between regular gift tissue paper and this really seems to help. After I do a seam or stitch, the tissue paper can just be ripped off and no one is the wiser. good luck!